Pair Name	Luteolin, Celecoxib
Disease Info	[ICD-11: 2C60]	Breast cancer		Investigative
Gene Regulation	Up-regulation	Expression	BAD	hsa572
	Up-regulation	Expression	BAK1	hsa578
	Up-regulation	Expression	BAX	hsa581
In Vitro Model	MCF-7	Invasive breast carcinoma of no special type	Homo sapiens (Human)	CVCL_0031
	MDA-MB-231	Breast adenocarcinoma	Homo sapiens (Human)	CVCL_0062
	SK-BR-3	Breast adenocarcinoma	Homo sapiens (Human)	CVCL_0033
In Vivo Model	MDA-MB-231 cells (2×10⁷) were inoculated subcutaneously into the right flanks of female BALB/c nude mice (6-7 weeks old)
Result	These results demonstrate the synergistic anti-tumor effect of the celecoxib and luteolin combination treatment in different four breast cancer cell lines, thus introducing the possibility of this combination as a new treatment modality.